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IUBMB Mid-Career Fellows
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ALL FELLOWSHIPS DEADLINE:
* APRIL 1st, 2021 *
Read more on Wood-Whelan Fellowships
Supports up to 4 months in a lab and up to a maximum of US $4,000 for travel expenses
Read more on Mid-Career Fellowships
Read more on Tang Education Fellowships
NEW Fellowships
https://iubmb.org/activities/
https://iubmb.org/activities/
IUBMB JOURNALS
Issue Highlights
- Toll‐like receptors (TLRs) in cancer; with an extensive focus on TLR agonists and antagonistsThe ability of Toll‐like receptors (TLRs) in distinguishing “self” and “non‐self” antigens is a cornerstone in the innate immunity system; however, their misregulation links inflammatory responses to the development of a wide range of human cancers. Generally, while chronic low‐grade TLR activation favors a tumor‐promoting state, high‐dose TLR activation induces antitumor responses. This issue sheds light on the controversial role of these receptors in human cancers as double‐edged swords, and further highlights the therapeutic efficacy of both TLR agonists and antagonists in cancer treatment strategies.
- Effects of different autophagy inhibitors on sensitizing KG‐1 and HL‐60 leukemia cells to chemotherapyAutophagy, a highly‐conserved catabolic process that is responsible for maintaining cell survival and homeostasis under different stressful conditions, is critically involved during chemotherapy with anti‐leukemic drugs, including arsenic trioxide (ATO) and/or all‐trans retinoic acid (ATRA). The blockade of autophagy flux at the late stages, especially with the lysosome inhibitor of hydroxyquinoline, rather than its total blockade using the early upstream inhibitor of 3‐Methyladenine, markedly potentiates anti‐leukemic and apoptotic effects of ATO/ATRA in KG1 leukemic stem‐like cells but not HL‐60 cells. The autophagy manipulation may enhance the effectiveness of chemotherapy in leukemia cells in a cell‐ and context‐dependent manner.
Introducing IUBMB Life’s new Editor-in-Chief: Efstathios S. Gonos
Efstathios S. Gonos began his new role as Editor-in-Chief of IUBMB Life
on January 1st, 2021.
Click here for more information
We would also like to welcome the new Associate Editors and Assistant Editor to IUBMB Life
Click here to see the Editorial Board
Issue Highlights
- Phytochemicals impact on osteogenic differentiation of mesenchymal stem cells
- Medicinal plants and bioactive natural compounds as inhibitors of HMG‐CoA reductase: A literature review
UPCOMING MEETING
General registration deadline until 29 January 2021 | https://annual-